AV comparison, www.av-comparatives.org has made a rather interesting comparison of how much different AV products slow down your machine, besides the technical comparison they also offer some general advices on how to optimize your experience with AV products in general..  Interesting reading, get their PDF here

A summery of their findings (higher is better);

  • AVIRA AntiVir Premium 9.0 – 199 point
  • Kingsoft Antivirus 9 Plus – 196 point
  • F-Secure Anti-Virus 2010 – 195 point
  • Kaspersky Anti-Virus 2010 – 193 point
  • Sophos Anti-Virus 9.0.1 – 193 point
  • Microsoft Security Essentials 1.0 – 190 point
  • avast! Free 5.0 – 188 point
  • Symantec Norton AntiVirus 2010 – 188 point
  • ESET NOD32 Antivirus 4.0 – 183 point
  • McAfee VirusScan Plus 2010 – 174 point
  • Norman Antivirus & AntiSpyware 7.30 – 169 point
  • AVG Anti-Virus 9.0 – 164 point
  • BitDefender Antivirus 2010 – 154 point
  • G DATA AntiVirus 2010 – 152 point
  • eScan AntiVirus 10.0 – 137 point
  • Trustport Antivirus 2010 – 125 point